Denis Betts has recalled Setaimata Sa to the 19-man squad to face Wigan.
Sa, who joined the Vikings from Hull FC in the off-season, has missed the last three matches through injury.
However the forward, who scored three tries in his opening three games for the club, is in contention to face the Warriors in Thursday’s top of the table contest.
Patrick Ah Van has dropped out of the squad to face Wigan, who have named an unchanged squad for the match.
Widnes’ 19-man squad to face Wigan: Brown, Cahill, Dean, Dudson, Gerrard, Gilmore, Hanbury, Heremaia, Houston, Leuluai, Manuokafoa, Marsh, Mellor, O’Carroll, Runciman, Sa, Thompson, White, Whitley.