Salford Red Devils will host Toronto Wolfpack in the fifth round of the Challenge Cup.
The Canadian club will get their first taste of competitive action against Super League opposition having progressed to the fifth round stage following victories over Siddal and London Broncos.
The game will see Brian Noble return to Salford after he was removed from his role as head coach in 2014.
Elsewhere, Leigh and Hull Kingston Rovers will face one another, just months after the Centurions replaced the Robins in Super League.
Doncaster have been handed the lucrative tie in the shape of a trip to Headingley to face Leeds, while the Heavy Woollen Derby will be showcased in cup action after Dewsbury were drawn at home to feirce rivals Batley.
There will also be at least one League 1 side in the last 16 of the competition after York City Knights were pitted against Barrow Raiders.
Challenge Cup fifth round draw:
Leigh Centurions v Hull Kingston Rovers
Featherstone Rovers v Oldham
Leeds Rhinos v Doncaster
Salford Red Devils v Toronto Wolfpack
Whitehaven/Oxford v Halifax
Dewsbury Rams v Batley Bulldogs
Huddersfield Giants v Swinton Lions
York City Knights v Barrow Raiders