Travis Burns and Atelea Vea will make their St Helens debuts this weekend, when the Super Leauge Champions take on Widnes in the traditional Karalius Cup clash this Sunday.
Jonny Lomax and Jon Wilkin are also set to feature in Keiron Cunningham’s side for the first time since lengthy injury layoffs, too.
Meanwhile, Lance Hohaia (suspended), Josh Jones, Luke Walsh, Louie McCarthy-Scarsbrook, Anthony Walker and Matty Fozard miss out through illness and injury.
St Helens squad to face Widnes:
1. Jonny Lomax, 2. Tommy Makinson, 3. Jordan Turner, 5. Adam Swift, 6. Travis Burns, 8. Mose Masoe, 9. James Roby, 10. Kyle Amor, 11. Atelea Vea, 12. Jon Wilkin, 14. Alex Walmsley, 15. Mark Flanagan, 17. Mark Percival, 18. Luke Thompson, 19. Greg Richards, 20. Paul Wellens, 21. Joe Greenwood, 22. Matty Dawson, 24. Jordan Hand, 25. Andre Savelio, 26. Lewis Charnock, 27. Dave Hewitt, 28. Jack Ashworth, 29. Olly Davies, 30. Matty Fleming.
Meanwhile, Widnes include Rhys Hanbury in their squad for the game, having missed the opening pre-season game against Warrington last week. Danny Tickle also features for the first time in pre-season.
Widnes squad to face St Helens:
1. Rhys Hanbury, 2. Paddy Flynn, 3. Cameron Phelps, 4. Stefan Marsh, 5. Patrick Ah Van, 6. Kevin Brown, 7. Joe Mellor, 9. Lloyd White, 10. Manase Manuokafoa, 12. Danny Tickle, 13. Hep Cahill, 14. Chris Dean, 17. Chris Clarkson, 19. Ben Kavanagh, 20. Declan Hulme, 21. Danny Craven, 22. Liam Carberry, 23. Phil Joseph, 24. Macgraff Leuluai, 25. Alex Gerrard, 27. Grant Gore, 28. Matt Whitley, 31. Ryan Ince, 33. Aaron Heremaia.