Leeds Rhinos are favourites with bookmakers to go on and win their first Challenge Cup trophy since 1999.
After impressively despatching St Helens 32-12 on Saturday, the Rhinos are 7/4 to go all the way.
Cup holders Wigan are second favourites at 2/1, Warrington Wolves are third at 4/1 and Castleford Tigers are fourth at 8/1.
Widnes Vikings (20/1) and Bradford Bulls (25/1) complete the Super League contingent, while Leigh Centurions (100/1) and Keighley Cougars (1,000/1) are the Championship’s outside hopes.
The draw for the sixth round of the Tetley’s Challenge Cup will be made live on the BBC News channel tonight (Monday) at around 6.30pm.
The quarter-finals take place on the weekend of June 7-8.
Total Rugby League understands that all four matches of the quarter-finals will be broadcast live, with two matches to be screened by the BBC and two by Sky Sports.